CST promotes alternative transportation through a variety of programs.
A scientific resource for the SWIRM protein domain containing information on structure, function, and binding to either DNA or acetylated lysine residues during chromatin remodeling.
Cell viability is a measure of the proportion of live, healthy cells within a population. Assays to assess cell viability measure metabolic activity, ATP content, cell proliferation, or membrane integrity.
Tau Protein and Neurofibrillary Tangles
Tau is a microtubule-associated protein found in neurons, and its function is to stabilize axonal microtubules. Hyperphosphorylated tau is a hallmark of several neurodegenerative diseases including Alzheimer’s disease.
Technical Support
Have a questions about a product, protocol, or experiment? Contact a CST scientist via phone, email, or by submitting the form below.
Technical Support
Technical support and customer service from Cell Signaling Technology.
Terms & Conditions
The terms and conditions in place from Cell Signaling Technology, Inc.
The CST Product Performance Guarantee
(Process Explanations)
The guarantee behind all of CST's antibody products, ensuring performance, lot-to-lot consistency, and application validation.
The Study of PI3K / Akt Signaling
Video Tutorial on PI3K / Akt Signaling created by CST on upstream stimuli and downstream effects on cellular events (autophagy, mTOR)
The Study of Stem Cells
Video training tutorial on stem cells covering pluripotency, differentiation, and lineage markers by CST Cell Signaling Technology
TIR Protein Domain
(Protein Domains)
A scientific resource for the TIR protein domain containing information on structure, function, and binding in TLR Signaling.
TKL Protein Kinase Group
(Kinome Diagram)
A kinome diagram showing the TKL group of protein kinases.
TMT Total Proteome Profiling Services
Profile protein abundance in cells and tissues using multiplexed sample labeling with Tandem Mass Tags and LC-MS/MS.
TPR Protein Domain
(Protein Domains)
A scientific resource for the TPR protein domain containing information on structure, function, and domain binding in cell cycle-associated proteins.
Trademark Information
Trademark information appearing on Cell Signaling Technology website.
TRAF Protein Domain
(Protein Domains)
A scientific resource for the TRAF protein domain containing information on structure, function, and domain binding in TNFR Signaling.
TREM2 Signaling Interactive Diagram
(Pathway Diagram)
Expert-reviewed diagram providing a current overview of the TREM2 pathway with references to its role in tumor development
TUBBY Protein Domain
(Protein Domains)
A scientific resource for the TUBBY protein domain containing information on structure, function, and domain binding to DNA and phospholipids.
TUDOR Protein Domain
(Protein Domains)
A scientific resource for the TUDOR protein domain containing information on structure, function, and domain binding to methylated-lysine residues in chromatin remodeling.
Tutorials & Application Guides
Video tutorials illustrate the science behind cellular processes and signaling pathways.
Types of ELISA (Enzyme-linked Immunosorbent Assay) Tests
Several types of ELISAs have been developed: direct ELISA, indirect ELISA, sandwich ELISA, competitive ELISA, multiplex ELISA. The types of ELISAs are categorized based on the type of antibodies and enzymes used to bind the antigen of interest.
Tyrosine Protein Kinases
(Kinome Diagram)
Graphical overview of the tyrosine kinase group of protein kinases featuring receptor and non-receptor (cytoplasmic) tyrosine kinases.
UBA Protein Domain
(Protein Domains)
A scientific resource for the UBA protein domain containing information on structure, function, and domain binding to ubiquitin in protein degradation pathways.
Ubiquitin and Ubiquitin-Like Protein Resources
(Pathway Diagram)
Expert-reviewed interactive pathway providing a current overview of protein ubiquitination and proteasome degradation, as well as links to products from Cell Signaling Technology.
Ubiquitin Ligase Table
(Table Resources)
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
UEV Protein Domain
(Protein Domains)
A scientific resource for the UEV protein domain containing information on structure, function, and domain binding to ubiquitin.
UIM Protein Domain
(Protein Domains)
A scientific resource for the UIM protein domain containing information on structure, function, and domain binding to ubiquitin.
Understand Protein Expression in Tissue with Immunohistochemistry (IHC)
(Application Overviews)
Learn how to visualize protein expression in tissue with immunohistochemistry (IHC). See examples of successfully optimized IHC assays.
Understanding Neurodegenerative (NDG) Diseases
Neurodegeneration refers to disorders of the CNS that lead to loss of neurons or glia, and is associated with age-related diseases, autoimmune attacks on the nervous system, or genetic mutations that affect the heath of CNS cells.
Understanding the Role of RNA Regulation and Epitranscriptomics in Disease
RNA Regulation, Epitranscriptomics, and Disease | Cell Signaling Technology
Validation for Histone Modification Antibodies
Histone modification antibodies are validated using a peptide array assay at CST
Vesicle Trafficking Video Tutorial
3D animated video of vesicle trafficking and intracellular protein transport
VHL Protein Domain
(Protein Domains)
A scientific resource for the VHL protein domain containing information on structure, function, and domain binding to hydroxylated proline residues.
VHS Protein Domain
(Protein Domains)
A scientific resource for the VHS protein domain containing information on structure, function, and domain binding.
Waste Management
Cell Signaling Technology finds way to reduce our waste through recycling programs.
WD40 Protein Domain
(Protein Domains)
A scientific resource for the WD40 protein domain containing information on structure, function, and binding to both phospho-Ser/Thr and methylated lysine residues.
We have a new URL! www.cellsignal.cn
We have a new URL! cellsignal.cn
Webinar - Deciphering immuno-oncology: Targeting innate immunity in cancer
This webinar will focus on how therapeutic interventions targeting dendritic cells can promote tumor immunity and enhance the efficacy of cancer therapy.
Webinar - Deciphering neurodegeneration: Inflammation, immune response, and Alzheimer's
This webinar will focus on the potential role of innate immunity in neurodegeneration and cognitive function, particularly in Alzheimer's disease.
Webinar - Mechanisms of Myeloid Immunosuppression: Functional Characterization of the Tumor Microenvironment Using Single and Multiplex IHC
This webinar will focus on the importance of the immune regulatory context of the TME
