A scientific resource for the CALM protein domain, also known as ANTH domain, containing information on structure, function, and binding to phospholipids.
A kinome diagram showing the CAMK group of protein kinases.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
Interact with this CAR-T signaling pathway to learn how the combination of extracellular and intracellular domains, including CD8, CD28, 4-1BB, OX40, or CD27, exert antitumor effects.
A scientific resource for the CARD protein domain containing information on structure, function, and domain binding during apoptosis.
CST offers flow validated antibodies for single cell mass cytometry (MC) and IHC validated antibodies for imaging mass cytometry (IMC)
Caspase-3 Activity Protocol: easy to follow directions describing the step by step experimental procedure.
Compare Cell Signaling Technology's Cleaved Caspase antibodies against one another to determine optimal applications.
Cleaved caspase-3 product listings, product citation lists,product selection tools, comparison tables and educational resources for apoptosis signaling from Cell Signaling Technology.
A scientific resource for the coiled coil (CC) protein domain containing information on structure, function, and domain binding.
A list of important CD markers that includes links to PhosphoSitePlus, Uniprot, and products from Cell Signaling Technology.
Overview of cell cycle and DNA damage signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources.
Overview of apoptosis signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources for apoptosis research.
Cellular Landscapes
(Cellular Landscapes)
A listing of interactive 3D molecular models displaying signal transduction pathways in the context of their cellular landscapes produced by Cell Signaling Technology.
Cellular Landscapes: Adhesion
(Cellular Landscapes)
Interactive 3D molecular model depicting key adhesion signaling pathway nodes within their cellular landscape and integrated with PhosphoSitePlus protein pages.
Cellular Landscapes: Mitochondria
Interactive 3D molecular model depicting the cellular landscape of mitochondria and it's various protein subsets including Apoptosis, Cytoskeleton, Warburg, etc.
Cellular Landscapes: Nucleus
An interactive 3D molecular model depicting the cellular landscape of a nucleus and it's various protein subsets including DNA Damage, Replication, Transcription, etc.
Cellular Landscapes: Protein Synthesis
(Cellular Landscapes)
Interactive 3D molecular model depicting key adhesion signaling pathway nodes within their cellular landscape and integrated with PhosphoSitePlus protein pages.
Cellular Landscapes: Receptor Tyrosine Kinase (RTK)
(Cellular Landscapes)
Interactive 3D molecular model depicting key RTK signaling pathways including c-Kit, EGFR, etc, and integrated with PhosphoSitePlus® protein pages.
Cellular Landscapes: Vesicle Trafficking
(Cellular Landscapes)
Interactive 3D molecular model depicting key Vesicle Trafficking nodes within their cellular landscape and integrated with PhosphoSitePlus protein pages.
Cellular Metabolism
(Pathway Diagram)
Overview of Cellular Metabolism pathways, antibodies and related reagents, interactive pathway diagrams, and other technical resources
Cellular Senescence
Cellular senescence is stable cell cycle arrest linked to aging and cancer and other disease states, including those associated with inflammation. It is induced by DNA damage, oncogenic signaling, and telomere shortening.
Certifications
Cell Signaling Technology, Inc. (CST) is ISO 9001:2008 certified for the design, development, and production of monoclonal antibodies (mAbs).
CH Protein Domain
(Protein Domains)
A scientific resource for the CH protein domain containing information on structure, function, and binding to phospho-serine and phospho-threonine motifs.
Changes to Recommended Western Blotting Protocols
(Protocols)
A demonstration of the perils of deviating from Cell Signaling Technology's recommended protocols.
ChIP Validated Antibodies and Primer Pairs
(Application Overviews)
SimpleChIP® Kits and Antibodies validated in-house by our antibody development scientists correlated to positive and negative control primers.
ChIP-seq Ab Performance Comparison
(Product Type Overviews)
ChIP-seq is a powerful technique that combines ChIP and next-generation sequencing (NGS) to study DNA-protein interactions across the entire genome, but it is only as good as the quality of the antibody used in the ChIP experiment.
ChIP-seq Validated Antibodies
ChIP-seq is a powerful technique that combines ChIP and next-generation sequencing (NGS) to study DNA-protein interactions across the entire genome, but it is only as good as the quality of the antibody used in the ChIP experiment.
ChIP-Sequencing performed using the SimpleChIP® Kit
(Application Overviews)
Use SimpleChIP kits to perform high throughput ChIP-Sequencing and assay genome wide changes in histone modifications and transcription factor binding.
Chromatin Immunoprecipitation (ChIP) Resource Center
(Application Overviews)
Comprehensive SimpleChIP® kits and ChIP validated antibodies from CST and validated ChIP reagents (primer pairs, Protein G agarose and magnetic beads
Chromatin Immunoprecipitation Technical Support
(Application Overviews)
Detailed technical support information to support ChIP experimental success. LInk to CST's comprehensive ChIP protocol.
Chromatin Immunoprecipitation Troubleshooting Guide
(Protocols)
Chromatin Immunoprecipitation Troubleshooting Guide: easy to follow directions describing the step by step experimental procedure.
Chromatin Immunoprecipitation Workflow Solutions for ChIP-qPCR and ChIP-seq
(Application Overviews)
Chromatin Immunoprecipitation Workflow Solutions for ChIP-qPCR and ChIP-seq
Chromatin IP Frequently Asked Questions
(Application Overviews)
Chromatin IP (ChIP) Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.
Chromo Protein Domain
(Protein Domains)
A scientific resource for the Chromo protein domain containing information on structure, function, and binding to methylated lysine residues during chromatin remodeling.
CK1 Protein Kinases Group
(Kinome Diagram)
A kinome diagram showing the CK1 family of protein kinases.
CMGC Protein Kinases Group
(Kinome Diagram)
A kinome diagram showing the CMGC group of protein kinases.
Commitment to Science
Summary description of CST with the mission statement and corporate commitment.
Common Pluripotency Markers
Highlighted common pluripotency markers with a brief description of their expression from Cell Signaling Technology
Community Garden and Pollinator Protection
CST has a backyard garden program for employees to participate in.
Community Grants
Grant application guidelines and project description criteria for funding from CST.
Community Investment
A list of non-profit organizations and communities who have received support from Cell Signaling Technology
Comparison Tables
Comparison tables for product research
Conferences & Events
Cell Signaling Technology events including the 2014 conference and vendor show listings.
Control Cell Extracts
Catalog numbers in tabular format for control cell extracts and proteins with links to product pages.
Control Treatments by Target
(Control Table)
A list of recommended cell types and treatments to be used as positive and negative controls for activation state specific antibodies
CSD Protein Domain
(Protein Domains)
A scientific resource for the CSD protein domain containing information on structure, function, and domain binding during chromatin remodeling.
CST Antibody Validation Principles
(Process Explanations)
Antibody validation principles at Cell Signaling Technology.
CST CUT&RUN Kit: Validated for Flexibility
Learn how we have validated and optimized our CUT&RUN Kit to yield better signal-to-noise ratios, require fewer cells to analyze protein-DNA interactions, and be compatible with tissue samples. Get up to speed on all the protocol improvements we have mad
CST Media Room
CST Media Room
CST Proteomics Inquiries
(Proteomics Overviews)
Fill out the form to contact the Proteomics Analytical Services team.
CST REMAINS OPEN DURING COVID-19 PANDEMIC
We Take Our Responsibility to You Seriously
CST Scientists Publish Results of Phosphoproteomic Study
Synopsis of CST scientists' publication in the journal Science Signaling describing phosphorylation patterns associated with non-small cell lung cancer (NSCLC).
CST Technical Documentation
Download the SDS, CoA, and Data Sheet for any CST product by searching with your CST product number.
CUE Protein Domain
(Protein Domains)
A scientific resource for the CUE protein domain containing information on structure, function, and domain binding to ubiquitin in protein degradation pathways.
Custom Conjugation & Labeling Services
Custom-build antibody conjugates that match your assay requirements and deliver superior performance, and choose from a broad catalog of labels.
Custom ELISA Kits and Matched Antibody Pairs
Choose custom CST® ELISA products to match your project needs. Reserve lots, customize volumes or kit formats, order custom-matched antibody pairs, and more.
Custom Formulations Request
Many of our products are available in custom formulations. CST is happy to work with you to tailor products to meet the specialized needs of your experiments.
Custom Product Pricing Request
Consistent with the CST pledge to be a research partner, CST offers custom pricing for reagents needed in your assay.
Customer Support
Have a questions about an order? Contact a CST scientist via phone, email, or by submitting the form below.
