Listing of IHC-related scientific posters and papers involving scientists from Cell Signaling Technology.
Parkinson’s Disease Resource Center
A scientific resource for the PAS protein domain containing information on structure, function, and domain binding.
PathScan ELISA kits detect endogenous levels of key signaling proteins using a traditional sandwich-based assay format in phospho-specific or total protein options.
PathScan® Sandwich ELISA Antibody Pair Protocol: easy to follow directions describing the step by step experimental procedure.
Protocol for PathScan® Chemiluminescent Sandwich ELISA (for kits with Lyophilized Antibodies)
PathScan® Sandwich ELISA Protocol (Chemiluminescent): easy to follow directions describing the step by step experimental procedure.
PathScan® Sandwich ELISA Protocol (for kits with Lyophilized Antibodies) from Cell Signaling Technology with recommended companion products.
PathScan® Sandwich ELISA Protocol Colormetric: easy to follow directions describing the step by step experimental procedure.
Pathways are grouped by research area and by disease area
Find Pathways and Diagrams By Disease Area
Resources include signaling pathways, antibodies and companion products, research overviews, technical resources, and recent review articles.
A scientific resource for the PB1 protein domain containing information on structure, function, and domain binding in cytoskeletal signaling proteins.
PD-L1/PD1 immune checkpoint helps tumor cells evade detection by the immune system. Highly specific and sensitive PD-L1 antibody now available from CST.
A scientific resource for the PDZ protein domain containing information on structure, function, and domain binding.
A scientific resource for the PH domain containing information on structure, function, and domain binding to phospholipids during protein trafficking and cell signaling.
Expert scientist-authored white paper focused on phosphorylation-dependent protein interaction domains in signal transduction.
Online systems biology resource for study of post-translational modifications: phosphorylation, ubiquitination, acetylation and methylation.
The Akt Binding Partners Table provides a list of proteins that bind to Akt along with their effects, activities, and corresponding PubMed reference(s).
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
Overview of PI3K/Akt signaling pathways, antibodies and related reagents, interactive pathway diagrams, and other technical resources.
A scientific resource for the POLO-Box protein domain containing information on structure, function, and domain binding to phospho-Ser/Thr motifs.
PTM Enrichment and Quantitation
This webinar will focus on the use of simultaneous affinity enrichment workflows by combining different PTM antibodies for ‘one-pot enrichment’ approaches
Scientific posters presented by CST scientists at various conferences and trade shows through the years.
Pre-Clinical IHC Tools for Mouse Models
The ELISA method has many variations, all of which rely on complex of an antigen and an antibody/enzyme conjugate. Signal is generated by turnover of substrate.
Privacy
The privacy policy currently in place from Cell Signaling Technology, Inc.
The privacy policy currently in place for California residents from Cell Signaling Technology, Inc.
Publications featuring Akt antibodies from Cell Signaling Technology.
Publications featuring Erk antibodies from Cell Signaling Technology.
If you have a suggestion for a new product, please fill out the form below. Our product team may contact you for more information about your needs.
A table that lists shelf-life expectations for CST products (when stored under the recommended conditions).
CST product packaging is based on feedback from customers as to the number of assays they typically run.
See the latest promotions, offers and specials for Cell Signaling Technology
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
A categorical list of protein domain resources by Cell Signaling Technology. Each resource contains specific domain structure, function, and binding information.
A list of antibodies directed against chaperones and other proteins involved in Protein Folding offered by Cell Signaling Technology.
An introduction to human protein kinases: protein kinases are key regulators of cell function.
CST® Proteomics Analytical Services help you identify and validate drug targets, discover biomarkers, determine on/off-target effects, and mechanisms of action.
PTMScan Technology enables biomarker discovery and signaling regulation by combining enrichment of post-translational modifications with mass spectrometry.
CST sponsored Science Webinar Series: Exploring Cell Signaling through Mass Spec: May 1, 2013. Hear the webinar (3 speakers), download slides and transcripts.
Use our protocol compatibility table to understand which immune signaling and phenotyping antibodies will work together in your multicolor flow cytometry experiment.
Protocol for Combined Staining of Intracellular Proteins and Cell Surface Markers in Blood: easy to follow directions describing the step by step experimental procedure.
Application protocols: easy to follow directions describing the step by step experimental procedure.
A scientific resource for the PTB protein domain containing information on structure, function, and domain binding to phospho-tyrosine motifs.
CST can identify and quantify thousands of post-translational modification sites specific to your sample—phosphorylation, ubiquitination, acetylation, and more.
Identifies and quantifies up to many hundreds of critical signaling nodes across pathways involved in cancer biology, immune cell signaling, and more.
PTMScan® Motif Antibody Kits from Cell Signaling Technology
Features, benefits, and product listing for PTMScan Direct Proteomic Services for the targeted screening of defined protein sites critical for drug and biomarker discovery.
A chronological listing of case studies and peer-reviewed publications utilizing PTMScan proteomic technology developed by Cell Signaling Technology.
A video tutorial illustrating the methodology behind PTMScan Technology and an example of its use in a recent phosphoproteomic study authored by scientists from CST.
PTMScan videos and links to complementary technologies for phospho-peptide enrichment and Science Webinar on Proteomics and Cell Signaling.
Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST, which allows for targeted screening of 100 proteins within defined pathways.
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST, which allows for targeted screening of 263 proteins within defined pathways.
Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein sites within the Ser/Thr kinome.
Information and case study data for the PTMScan Direct Tyrosine Kinases Service, which allows for the targeted screening of a defined set of protein sites within the tyrosine kinome.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
A comprehensive list of CST scientist authored publications.
A scientific resource for the PUF (Pumilio) protein domain containing information on structure, function, and domain binding to regulate mRNA stability during development.
A scientific resource for the PWWP protein domain containing information on structure, function, and domain binding.
A scientific resource for the PX protein domain containing information on structure, function, and domain binding to phospholipids.
Listing of reference table resources for cellular regulation and signaling research
Stem cell markers and kits organized in table format: links to product pages; includes Oct-4, Sox2, Nanog, c-Myc, C/EBPα, LIN28 and KLF4.
User form to request permission to use any CST pathway or diagram. Requests are reviewed and/or approved by CST Marketing.
Resazurin Cell Viability Kit Protocol: easy to follow directions describing the step by step experimental procedure.
CST’s does not ship in styrofoam coolers and packaging materials are recyclable.
Request for review of CST products used in customer research application. CST wants your feedback.
A scientific resource for the RGS protein domain containing information on structure, function, and domain binding during G protein-mediated signaling.
Rheumatoid Arthritis Pathogenesis | Cell Signaling Technology (CST)
A scientific resource for the RING protein domain containing information on structure, function, and domain binding to ubiquitin in protein degradation pathways.
Discover the key RNA binding proteins (RBPs) in the lifecycle of messenger RNA (mRNA)
Resources for the study of Translational Control, Protein Synthesis, and RNA Regulation including antibodies and associated reagents, interactive pathway diagrams, and other technical resources.
Safety Data Sheets (formerly known as MSDS sheets) are downloadable from CST in PDF format.
Contact your local sales department using the phone number or form below, and you will receive a reply within 24 hours.
A scientific resource for the SAM protein domain containing information on structure, function, and domain binding.
Links to sample preparation protocols: provided in pdf format (9-15 page documents).
Links for scientific research at CST: open for all contributions by users of the library.
CST commitment to being your research partner: underscores this commitment with links to all available resources.
A collection of website featuring signal transduction research, disease and mutation databases, and online publication resources.
Expert-reviewed diagram providing a current overview of the Senescence Signaling pathway with references to its role in cell cycle
Learn more about new lab startup discounts at Cell Signaling Technology.
A scientific resource for the SH2 protein domain containing information on structure, function, and domain binding to phospho-tyrosine motifs.
A scientific resource for the SH3 protein domain containing information on structure, function, and domain binding to proline-rich motifs.
CST provides multiple options for avoiding the problems of traditional sonication protocols, which require subjecting chromatin to harsh, denaturing conditions that can damage both antibody epitopes and the integrity of the chromatin.
Assay Kits from CST contain ChIP validated antibodies and control PCR primers to assay for pluripotency markers or epigenetic mark status in human or mouse samples.
SimpleChIP® Chromatin Immunoprecipitation Protocol (Agarose Beads): easy to follow directions describing the step by step experimental procedure.
SimpleChIP® Chromatin Immunoprecipitation Protocol (Magnetic Beads): easy to follow directions describing the step by step experimental procedure.
SimpleChIP® Plus Chromatin Immunoprecipitation Protocol (Agarose Beads): easy to follow directions describing the step by step experimental procedure.a
SimpleChIP® Plus Chromatin Immunoprecipitation Protocol (Magnetic Beads): easy to follow directions describing the step by step experimental procedure.
SimpleChIP® Plus Sonication Chromatin Immunoprecipitation Protocol (Magnetic Beads): easy to follow directions describing the step by step experimental procedure
A scientific resource for the SNARE protein domain containing information on structure, function, and binding to mediate protein-protein interactions in vesicle trafficking.
A scientific resource for the SOCS Box protein domain containing information on structure, function, and domain binding during protein degradation pathways.
Get the reagents and supplies for immunohistochemistry (IHC) protocols including antibodies, diluent, blocking buffer, chromogens, and controls
Sonication ChIP Kit Performance Comparison
A scientific resource for the SPRY protein domain containing information on structure, function, and domain binding.
As a new antibody is developed, Cell Signaling Technology (CST) scientists test the antibody’s stability and activity
A scientific resource for the START protein domain containing information on structure, function, and domain binding.
Kinome diagram showing the STE group of protein kinases.
Overview of stem cell markers, lineage markers, development and differentiation signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources.
The ESC and Lineage Markers diagram provides an overview of ESC differentiation along lineage-specific pathways and links to products from CST.
CST believes in a data driven approach to continuous improvement and implementation of business practices that minimize negative impact on nature.}{icon: sustainability
CST promotes alternative transportation through a variety of programs.
A scientific resource for the SWIRM protein domain containing information on structure, function, and binding to either DNA or acetylated lysine residues during chromatin remodeling.
Cell viability is a measure of the proportion of live, healthy cells within a population. Assays to assess cell viability measure metabolic activity, ATP content, cell proliferation, or membrane integrity.
Tau is a microtubule-associated protein found in neurons, and its function is to stabilize axonal microtubules. Hyperphosphorylated tau is a hallmark of several neurodegenerative diseases including Alzheimer’s disease.
Technical support and customer service from Cell Signaling Technology.
Have a questions about a product, protocol, or experiment? Contact a CST scientist via phone, email, or by submitting the form below.
The terms and conditions in place from Cell Signaling Technology, Inc.
The guarantee behind all of CST's antibody products, ensuring performance, lot-to-lot consistency, and application validation.
Video Tutorial on PI3K / Akt Signaling created by CST on upstream stimuli and downstream effects on cellular events (autophagy, mTOR)
Video training tutorial on stem cells covering pluripotency, differentiation, and lineage markers by CST Cell Signaling Technology
A scientific resource for the TIR protein domain containing information on structure, function, and binding in TLR Signaling.
A kinome diagram showing the TKL group of protein kinases.
Profile protein abundance in cells and tissues using multiplexed sample labeling with Tandem Mass Tags and LC-MS/MS.