CST® Proteomics Analytical Services help you identify and validate drug targets, discover biomarkers, determine on/off-target effects, and mechanisms of action.
PTMScan Technology enables biomarker discovery and signaling regulation by combining enrichment of post-translational modifications with mass spectrometry.
CST sponsored Science Webinar Series: Exploring Cell Signaling through Mass Spec: May 1, 2013. Hear the webinar (3 speakers), download slides and transcripts.
Use our protocol compatibility table to understand which immune signaling and phenotyping antibodies will work together in your multicolor flow cytometry experiment.
Protocol for Combined Staining of Intracellular Proteins and Cell Surface Markers in Blood: easy to follow directions describing the step by step experimental procedure.
Application protocols: easy to follow directions describing the step by step experimental procedure.
A scientific resource for the PTB protein domain containing information on structure, function, and domain binding to phospho-tyrosine motifs.
CST can identify and quantify thousands of post-translational modification sites specific to your sample—phosphorylation, ubiquitination, acetylation, and more.
Identifies and quantifies up to many hundreds of critical signaling nodes across pathways involved in cancer biology, immune cell signaling, and more.
PTMScan® Motif Antibody Kits from Cell Signaling Technology
Features, benefits, and product listing for PTMScan Direct Proteomic Services for the targeted screening of defined protein sites critical for drug and biomarker discovery.
A chronological listing of case studies and peer-reviewed publications utilizing PTMScan proteomic technology developed by Cell Signaling Technology.
A video tutorial illustrating the methodology behind PTMScan Technology and an example of its use in a recent phosphoproteomic study authored by scientists from CST.
PTMScan videos and links to complementary technologies for phospho-peptide enrichment and Science Webinar on Proteomics and Cell Signaling.
Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST, which allows for targeted screening of 100 proteins within defined pathways.
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST, which allows for targeted screening of 263 proteins within defined pathways.
Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein sites within the Ser/Thr kinome.
Information and case study data for the PTMScan Direct Tyrosine Kinases Service, which allows for the targeted screening of a defined set of protein sites within the tyrosine kinome.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
A comprehensive list of CST scientist authored publications.
A scientific resource for the PUF (Pumilio) protein domain containing information on structure, function, and domain binding to regulate mRNA stability during development.