A scientific resource for the C1 protein domain containing information on structure, function, and binding to phospholipids.
A scientific resource for the C2 protein domain containing information on structure, function, and binding to phospholipids.
A scientific resource for the CALM protein domain, also known as ANTH domain, containing information on structure, function, and binding to phospholipids.
A kinome diagram showing the CAMK group of protein kinases.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
Interact with this CAR-T signaling pathway to learn how the combination of extracellular and intracellular domains, including CD8, CD28, 4-1BB, OX40, or CD27, exert antitumor effects.
A scientific resource for the CARD protein domain containing information on structure, function, and domain binding during apoptosis.
CST offers flow validated antibodies for single cell mass cytometry (MC) and IHC validated antibodies for imaging mass cytometry (IMC)
Caspase-3 Activity Protocol: easy to follow directions describing the step by step experimental procedure.
Compare Cell Signaling Technology's Cleaved Caspase antibodies against one another to determine optimal applications.
Cleaved caspase-3 product listings, product citation lists,product selection tools, comparison tables and educational resources for apoptosis signaling from Cell Signaling Technology.
A scientific resource for the coiled coil (CC) protein domain containing information on structure, function, and domain binding.
A list of important CD markers that includes links to PhosphoSitePlus, Uniprot, and products from Cell Signaling Technology.
Overview of cell cycle and DNA damage signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources.
Overview of apoptosis signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources for apoptosis research.
Cell Signaling Technology, Inc. Acquires BIOKÉ, B.V. and Expands Operations to Europe
(News Article)
Cell Signaling Technology, Inc. Develops Novel Monoclonal Antibody Discovery Platform
(News Article)
Cellular Landscapes
(Cellular Landscapes)
A listing of interactive 3D molecular models displaying signal transduction pathways in the context of their cellular landscapes produced by Cell Signaling Technology.
Cellular Landscapes: Adhesion
(Cellular Landscapes)
Interactive 3D molecular model depicting key adhesion signaling pathway nodes within their cellular landscape and integrated with PhosphoSitePlus protein pages.
Cellular Landscapes: Mitochondria
Interactive 3D molecular model depicting the cellular landscape of mitochondria and it's various protein subsets including Apoptosis, Cytoskeleton, Warburg, etc.
Cellular Landscapes: Nucleus
An interactive 3D molecular model depicting the cellular landscape of a nucleus and it's various protein subsets including DNA Damage, Replication, Transcription, etc.
Cellular Landscapes: Protein Synthesis
(Cellular Landscapes)
Interactive 3D molecular model depicting key adhesion signaling pathway nodes within their cellular landscape and integrated with PhosphoSitePlus protein pages.
Cellular Landscapes: Receptor Tyrosine Kinase (RTK)
(Cellular Landscapes)
Interactive 3D molecular model depicting key RTK signaling pathways including c-Kit, EGFR, etc, and integrated with PhosphoSitePlus® protein pages.
Cellular Landscapes: Vesicle Trafficking
(Cellular Landscapes)
Interactive 3D molecular model depicting key Vesicle Trafficking nodes within their cellular landscape and integrated with PhosphoSitePlus protein pages.
Cellular Metabolism
(Pathway Diagram)
Overview of Cellular Metabolism pathways, antibodies and related reagents, interactive pathway diagrams, and other technical resources
Cellular Senescence
Cellular senescence is stable cell cycle arrest linked to aging and cancer and other disease states, including those associated with inflammation. It is induced by DNA damage, oncogenic signaling, and telomere shortening.
Certifications
Cell Signaling Technology, Inc. (CST) is ISO 9001:2008 certified for the design, development, and production of monoclonal antibodies (mAbs).
CH Protein Domain
(Protein Domains)
A scientific resource for the CH protein domain containing information on structure, function, and binding to phospho-serine and phospho-threonine motifs.
Changes to Recommended Western Blotting Protocols
(Protocols)
A demonstration of the perils of deviating from Cell Signaling Technology's recommended protocols.
ChIP Validated Antibodies and Primer Pairs
(Application Overviews)
SimpleChIP® Kits and Antibodies validated in-house by our antibody development scientists correlated to positive and negative control primers.
ChIP-seq Ab Performance Comparison
(Product Type Overviews)
ChIP-seq is a powerful technique that combines ChIP and next-generation sequencing (NGS) to study DNA-protein interactions across the entire genome, but it is only as good as the quality of the antibody used in the ChIP experiment.
ChIP-seq Validated Antibodies
ChIP-seq is a powerful technique that combines ChIP and next-generation sequencing (NGS) to study DNA-protein interactions across the entire genome, but it is only as good as the quality of the antibody used in the ChIP experiment.
ChIP-Sequencing performed using the SimpleChIP® Kit
(Application Overviews)
Use SimpleChIP kits to perform high throughput ChIP-Sequencing and assay genome wide changes in histone modifications and transcription factor binding.
Chromatin Immunoprecipitation (ChIP) Resource Center
(Application Overviews)
Comprehensive SimpleChIP® kits and ChIP validated antibodies from CST and validated ChIP reagents (primer pairs, Protein G agarose and magnetic beads
Chromatin Immunoprecipitation Technical Support
(Application Overviews)
Detailed technical support information to support ChIP experimental success. LInk to CST's comprehensive ChIP protocol.
Chromatin Immunoprecipitation Troubleshooting Guide
(Protocols)
Chromatin Immunoprecipitation Troubleshooting Guide: easy to follow directions describing the step by step experimental procedure.
Chromatin Immunoprecipitation Workflow Solutions for ChIP-qPCR and ChIP-seq
(Application Overviews)
Chromatin Immunoprecipitation Workflow Solutions for ChIP-qPCR and ChIP-seq
