Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Information on KinomeView western blotting service offered by Cell Signaling Technology that uses Phospho-Motif Antibodies to provide a kinome-wide view of cellular phosphorylation.
KinomeView® Protocol: easy to follow directions describing the step by step experimental procedure.
Overview of PTMScan technology for proteomics from CST. Antibody enrichment of PTM peptides combined with mass spectrometry.
Find educational resources related to science or get technical support help with a product.
This webinar recording focuses on how to optimize two steps in the immunohistochemistry protocol. Antigen retrieval is required to reverse chemical crosslinks that can prevent antibodies from accessing their epitopes; the conditions of the primary antibo
The home office of CST is a LEED certified building.
A scientific resource for the LIM protein domain containing information on structure, function, and domain binding to mediate protein-protein interactions.
Ensure equal sample loading with loading control antibodies from CST.
A scientific resource for the LRR protein domain containing information on structure, function, and domain binding to mediate protein-protein interactions.
Expert-reviewed diagram providing a current overview of the m6A RNA pathway with references to its role in tumor development
Overview of MAP Kinase signaling pathways, antibodies and related reagents, interactive pathway diagrams, and other technical resources.
Mastering Phospho-Flow: Immune Cell Activation
To characterize activation of immune cells, measurement of intracellular signaling using phospho-specific antibodies combined with immune phenotyping using surface markers is ideal.
MBT Protein Repeat
(Protein Domains)
A scientific resource for the MBT protein domain containing information on structure, function, and binding to methyl-lysine motifs during chromatin regulation.
Mechanisms of Fibrosis
(Pathway Diagram)
Expert-reviewed diagram providing a current overview of the Mechanisms of Fibrosis pathway with references to its role in adhesion
Membrane-Enriched Total Proteome Service
Identify and quantify membrane proteins in a total proteome study for a more complete view of proteins on the cell surface.
Metabolic Changes in Cancer: The Warburg Effect
CST sponsored Science Webinar Series: Metabolic Changes in Cancer: April 19, 2012. Hear the webinar (3 speakers), download slides and transcripts.
MH2 Protein Domain
(Protein Domains)
A scientific resource for the MH2 protein domain containing information on structure, function, and domain binding to phospho-serine motifs during TGF-beta signaling.
MIU Protein Domain
(Protein Domains)
A scientific resource for the MIU protein domain containing information on structure, function, and domain binding to ubiquitin during vesicle trafficking.
Motif Antibodies for PTMScan® Discovery Services
(Proteomics Overviews)
A listing of PTMScan Motif Antibodies and Kits, along with case study data for each, for customers who purchase a license and would like to perform PTMScan Proteomics in-house.
Mouse Immune Cell Marker Guide
(Pathway Diagram)
This interactive guide shows the most important cell and functional state markers for tumor-infiltrating immune cells in mice.
Multiplex IHC
Fluorescent multiplex IHC (mIHC) with tyramide signal amplification enables simultaneous detection of multiple proteins in formalin-fixed paraffin-embedded (FFPE) tissue sections in a sequential fashion.
Multiplex Oligos for Illumina® Protocol (Dual Index Primers) (ChIP-seq, CUT&RUN)
(Protocols)
Multiplex Oligos for Illumina® Protocol (Dual Index Primers) (ChIP-seq, CUT&RUN): easy to follow directions describing the step by step experimental procedure.
Multiplex Oligos for Illumina® Protocol (Single Index Primers) (ChIP-seq, CUT&RUN)
(Protocols)
Multiplex Oligos for Illumina® Protocol (Single Index Primers) (ChIP-seq, CUT&RUN): easy to follow directions describing the step by step experimental procedure.a
Neural and Glial Cell Markers
There are a number of markers that can be used to distinguish the many cell types of the central and peripheral nervous system during development, adult neurogenesis, and the pathogenesis of neurodegenerative disorders.
Neuroinflammation in Neurodegenerative Diseases
Neuroinflammation is the activation of an immune response in the CNS by the microglia and astrocytes. While not linked mechanistically to neurodegenerative diseases, neuroinflammation is associated with the progression of Alzheimer's disease, Parkinson's
Neuronal and Glial Cell Markers
(Pathway Diagram)
Expert-reviewed interactive diagrams providing current overviews of neuronal and glial cell markers, as well as links to products from CST.
Neuroscience
(Pathway Diagram)
Expert-reviewed interactive neuroscience pathways providing current overviews of Parkinsons and Alzheimers Disease signaling, as well as links to products from CST.
Neurotransmitters, Receptors, and Transporters
Modulation of CNS function occurs through synaptic neurotransmission, which is the signaling from the axon terminal of one neuron to the dendrites of another via molecules called neurotransmitters.
Nuclear Permeabilization Staining
(Protocols)
Nuclear Permeabilization Staining: easy to follow directions describing the step by step experimental procedure.
Nuclear Receptors
(Pathway Diagram)
Expert-reviewed interactive pathway providing a current overview of Nuclear Receptor Signaling, a pathway description, select PubMed references, and links to PhosphoSitePlus.
NZF Protein Domain
(Protein Domains)
A scientific resource for the NZF protein domain containing information on structure, function, and domain binding to ubiquitin.
Optimizing the ELISA (Enzyme-Linked Immunosorbent Assay) Test
Optimization is critical to obtaining reliable ELISA results. The design and development of an ELISA assay depends on the various components, including capture antibody, blocking buffer, diluent, sample concentration, and detection antibody
Organelle Markers
(Application Overviews)
Organelle markers for immunofluorescence analysis from CST Cell Signaling Technology
Other Protein Kinases Group
(Kinome Diagram)
Kinome diagram showing "other" group kinases.
Our Approach/Process
Learn more about our approach to science and process for creating the best antibodies in the industry
Overview of Chromatin Immunoprecipitation (ChIP)
(Application Overviews)
Chromatin immunoprecipitation, or ChIP, is a technique that uses antibodies to isolate specific DNA-binding proteins along with the bound DNA fragments from cells and tissues.
Overview of Chromatin IP Assay Methodology
(Application Overviews)
The chromatin immunoprecipitation (ChIP) assay is a powerful and versatile technique to probe protein-DNA interactions within the natural chromatin context of the cell.
Overview of Immunostaining
Immunofluorescence (IF) techniques combine antibodies and fluorescence imaging to visualize biomolecules within fixed cell or tissue samples. This page answers common protocol questions to help your IF experiment be successful.
Overview of Metabolism and Metabolic Disorders
Metabolism defines all of the chemical changes or processes within cells, tissues, and organisms that sustain cellular homeostasis.
NF-κB Signaling
(Pathway Diagram)
p38 MAPK Signaling
(Pathway Diagram)