CST® Proteomics Analytical Services help you identify and validate drug targets, discover biomarkers, determine on/off-target effects, and mechanisms of action.
PTMScan Technology enables biomarker discovery and signaling regulation by combining enrichment of post-translational modifications with mass spectrometry.
CST sponsored Science Webinar Series: Exploring Cell Signaling through Mass Spec: May 1, 2013. Hear the webinar (3 speakers), download slides and transcripts.
Use our protocol compatibility table to understand which immune signaling and phenotyping antibodies will work together in your multicolor flow cytometry experiment.
Protocol for Combined Staining of Intracellular Proteins and Cell Surface Markers in Blood: easy to follow directions describing the step by step experimental procedure.
Application protocols: easy to follow directions describing the step by step experimental procedure.
A scientific resource for the PTB protein domain containing information on structure, function, and domain binding to phospho-tyrosine motifs.
CST can identify and quantify thousands of post-translational modification sites specific to your sample—phosphorylation, ubiquitination, acetylation, and more.
Identifies and quantifies up to many hundreds of critical signaling nodes across pathways involved in cancer biology, immune cell signaling, and more.
PTMScan® Motif Antibody Kits from Cell Signaling Technology
Features, benefits, and product listing for PTMScan Direct Proteomic Services for the targeted screening of defined protein sites critical for drug and biomarker discovery.
A chronological listing of case studies and peer-reviewed publications utilizing PTMScan proteomic technology developed by Cell Signaling Technology.
A video tutorial illustrating the methodology behind PTMScan Technology and an example of its use in a recent phosphoproteomic study authored by scientists from CST.
PTMScan videos and links to complementary technologies for phospho-peptide enrichment and Science Webinar on Proteomics and Cell Signaling.
Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST, which allows for targeted screening of 100 proteins within defined pathways.
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST, which allows for targeted screening of 263 proteins within defined pathways.
Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein sites within the Ser/Thr kinome.
Information and case study data for the PTMScan Direct Tyrosine Kinases Service, which allows for the targeted screening of a defined set of protein sites within the tyrosine kinome.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
A comprehensive list of CST scientist authored publications.
A scientific resource for the PUF (Pumilio) protein domain containing information on structure, function, and domain binding to regulate mRNA stability during development.
A scientific resource for the PWWP protein domain containing information on structure, function, and domain binding.
A scientific resource for the PX protein domain containing information on structure, function, and domain binding to phospholipids.
Listing of reference table resources for cellular regulation and signaling research
Reprogramming Factor Antibodies
Stem cell markers and kits organized in table format: links to product pages; includes Oct-4, Sox2, Nanog, c-Myc, C/EBPα, LIN28 and KLF4.
Request Permission for Pathway or Diagram
User form to request permission to use any CST pathway or diagram. Requests are reviewed and/or approved by CST Marketing.
Resazurin Cell Viability Kit Protocol
(Protocols)
Resazurin Cell Viability Kit Protocol: easy to follow directions describing the step by step experimental procedure.
Responsible Marketing and Packaging
CST’s does not ship in styrofoam coolers and packaging materials are recyclable.
Review Your Recent CST Purchase
Request for review of CST products used in customer research application. CST wants your feedback.
RGS Protein Domain
(Protein Domains)
A scientific resource for the RGS protein domain containing information on structure, function, and domain binding during G protein-mediated signaling.
Rheumatoid Arthritis Pathogenesis Signaling Pathway
(Pathway Diagram)
Rheumatoid Arthritis Pathogenesis | Cell Signaling Technology (CST)
RING Protein Domain
(Protein Domains)
A scientific resource for the RING protein domain containing information on structure, function, and domain binding to ubiquitin in protein degradation pathways.
RNA Lifecycle Interactive Diagram
(Pathway Diagram)
Discover the key RNA binding proteins (RBPs) in the lifecycle of messenger RNA (mRNA)
RNA Regulation, Translational Control, and Protein Synthesis
(Pathway Diagram)
Resources for the study of Translational Control, Protein Synthesis, and RNA Regulation including antibodies and associated reagents, interactive pathway diagrams, and other technical resources.
Safety Data Sheet (SDS)
Safety Data Sheets (formerly known as MSDS sheets) are downloadable from CST in PDF format.
Sales Department
Contact your local sales department using the phone number or form below, and you will receive a reply within 24 hours.
SAM Protein Domain
(Protein Domains)
A scientific resource for the SAM protein domain containing information on structure, function, and domain binding.
Sample Preparation Protocols
Links to sample preparation protocols: provided in pdf format (9-15 page documents).
Regulation of Actin Dynamics
(Pathway Diagram)
Regulation of Apoptosis
(Pathway Diagram)
Regulation of eIF2
(Pathway Diagram)
Regulation of eIF4E and p70 S6 Kinase
(Pathway Diagram)
SAPK/JNK Signaling Cascades
(Pathway Diagram)