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Histone Modification Table (Table Resources)

The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.

How Does PTMScan® Direct Proteomic Service Work? (Proteomics Overviews)

Overview of methodology and client deliverables for the PTMScan Direct Proteomic Service offered by Cell Signaling Technology.

How to Analyze Multiple Markers in Tissue Samples Using Multiplex IHC

Multiplex immunohistochemistry (mIHC): Perform in depth tissue analysis on a single slide to understand protein co-localization and spatial context

How to Choose Enzymatic or Sonication Protocol for ChIP

This webinar will focus on the importance of the immune regulatory context of the TME

How We Select Our Antibody Targets (Process Explanations)

How CST responds to customer feedback as it relates to development of the product portfolio.

HRP Chemiluminescence ELISA-P (Protocols)

HRP Chemiluminescence ELISA-Pl: easy to follow directions describing the step by step experimental procedure.

Human Immune Cell Marker Guide (Pathway Diagram)

This interactive guide shows the key cell and functional state markers for tumor-infiltrating immune cells in humans.Web Location: Immunology and Inflammation

Human Oncogenes & Tumor Suppressor Genes (Table Resources)

Summary of human oncogenes and tumor suppressor genes sorted by signaling pathway.

Human Protein Kinases Overview (Kinome Diagram)

Interactive kinome diagram of the human protein kinases.

Human Tyrosine Protein Kinases (Kinome Diagram)

A kinome diagram showing the human tyrosine kinase group. This group of protein kinases comprises receptor and non-receptor tyrosine kinases.

IMAC Service (Proteomics Overviews)

Quantitating Ser/Thr phosphorylation by Immobilized Metal Affinity Chromatography enrichment and analysis identifies thousands of sites with minimal sample.

Immobilized Immunoprecipitation Protocol / (For Analysis By Western Immunoblotting) (Protocols)

Immobilized IP Protocol / (For Analysis By Western Blot): easy to follow directions describing the step by step experimental procedure.Immobilized IP Protocol / (For Analysis By Western Blot): easy to follow directions describing the step by step experim

Immuno-Parallel Reaction Monitoring (iPRM) (Proteomics Overviews)

iPRM is a multiplexed LC/MS assay service that combines the specificity of mass spectrometry, the throughput of an immunoassay, and the power of multiplexing to accelerate the time-to-market of your drug and/or diagnostic test.

Immunofluorescence (IF) Resource Center (Application Overviews)

Immunofluorescence-validated antibodies from CST Cell Signaling Technology

Immunofluorescence (IF) Troubleshooting Guide

A helpful guide to help answer questions and troubleshoot common problems encountered in immunofluorescence.

Immunofluorescence Protocol for Biotin-Conjugated Antibodies (Protocols)

Immunofluorescence Protocol for Biotin-Conjugated Antibodies: easy to follow directions describing the step by step experimental procedure.

Immunofluorescence Protocol for Cell-based Assays Requiring Methanol Fixation (Protocols)

Immunofluorescence Protocol wit Methanol Fixation (IF Methanol-fixed): easy to follow directions describing the step by step experimental procedure.Immunofluorescence Protocol for Methanol Fixation (IF Methanol-fixed): easy to follow directions describin

Immunofluorescence Protocol for Labeling with BrdU Antibody (Protocols)

Immunofluorescence Protocol for Labeling with BrdU Antibody: easy to follow directions describing the step by step experimental procedure.

Immunofluorescence Protocol with DOTMAC Permeabilization (Protocols)

Immunofluorescence Protocol with DOTMAC Permeabilization: easy to follow directions describing the step by step experimental procedure.Immunofluorescence Protocol with DOTMAC Permeabilization: easy to follow directions describing the step by step experim

Immunofluorescence Protocol with Formaldehyde Fixation (Protocols)

Immunofluorescence General Protocol: easy to follow directions describing the step by step experimental procedure.Immunofluorescence General Protocol: easy to follow directions describing the step by step experimental procedure.

Immunofluorescence Protocol with Gelatin Blocking Step (Protocols)

Immunofluorescence Protocol with Gelatin Blocking Step: easy to follow directions describing the step by step experimental procedure.Immunofluorescence Protocol with Gelatin Blocking Step: easy to follow directions describing the step by step experimenta

Immunofluorescence Protocol with Image-iT™ FX Signal Enhancer (Protocols)

Immunofluorescence Protocol with Image-iT™ FX Signal Enhancer: easy to follow directions describing the step by step experimental procedure.Immunofluorescence Protocol with Image-iT™ FX Signal Enhancer: easy to follow directions describing the step by st

Immunofluorescence Protocol with Methanol Permeabilization (IF Methanol-perm) (Protocols)

Immunofluorescence Protocol with Methanol Permeabilization: easy to follow directions describing the step by step experimental procedure.Immunofluorescence Protocol with Methanol Permeabilization: easy to follow directions describing the step by step exp

Immunofluorescence Protocol with n-Octyl-Glucoside PermeabilizationTechnology (Protocols)

Immunofluorescence Protocol with n-Octyl-Glucoside Permeabilization: easy to follow directions describing the step by step experimental procedure.Immunofluorescence Protocol with n-Octyl-Glucoside Permeabilization: easy to follow directions describing th

Immunofluorescence Protocol with Saponin Permeabilization (Protocols)

Immunofluorescence Protocol with Saponin Permeabilization: easy to follow directions describing the step by step experimental procedure.

Immunofluorescence Protocol without Permeabilization (Protocols)

Immunofluorescence Protocol without Permeabilization: easy to follow directions describing the step by step experimental procedure.

Immunofluorescence Protocol – Specific for Product: 2187 (Protocols)

Immunofluorescence Protocol – Specific for Product: 2187: easy to follow directions describing the step by step experimental procedure.

Immunofluorescence Technical Support (Protocols)

Immunofluorescence Technical Support | CST Cell Signaling Technology

Immunohistochemical Analysis

Learn how to best interpret IHC staining and understand experiment results accurately.

Immunohistochemistry (IHC) Troubleshooting Guide & the Importance of Using Controls (Protocols)

Learn how to best interpret IHC staining and understand experiment results accurately.

Immunohistochemistry Leica® BOND™ Protocol (Protocols)

Immunohistochemistry Leica® Bond™ Protocol: easy to follow directions describing the step by step experimental procedure.

Immunohistochemistry Protocol (Frozen) (Protocols)

Immunohistochemistry Protocol (Frozen): easy to follow directions describing the step by step experimental procedure.

Immunohistochemistry Protocol (Frozen) – Specific for Product: 4060 (Protocols)

Immunohistochemistry Protocol (Frozen) – Specific for Product: 4060: easy to follow directions describing the step by step experimental procedure.

Immunohistochemistry Protocol (Paraffin) (Protocols)

Immunohistochemistry Protocol (Paraffin): easy to follow directions describing the step by step experimental procedure.Immunohistochemistry Protocol (Paraffin): easy to follow directions describing the step by step experimental procedure.

Immunohistochemistry Protocol (Paraffin) - Specific For Product: 3287 (Protocols)

Immunohistochemistry Protocol (Paraffin): easy to follow directions describing the step by step experimental procedure.

Immunohistochemistry Protocol (Paraffin) - Specific For Product: 3625 (Protocols)

Immunohistochemistry Protocol (Paraffin): easy to follow directions describing the step by step experimental procedure.

Immunohistochemistry Protocol (Paraffin) - Specific For Product: 3633 (Protocols)

Immunohistochemistry Protocol (Paraffin): easy to follow directions describing the step by step experimental procedure.

Immunohistochemistry Protocol (Paraffin) - Specific for Product: 9319 (Protocols)

Immunohistochemistry Protocol (Paraffin) - Specific for Product: easy to follow directions describing the step by step experimental procedure.

Immunohistochemistry Protocol (Paraffin) - Specific For Products: 2085, 3197 (Protocols)

Immunohistochemistry Protocol (Paraffin) - Specific For Products: 2085, 3197: easy to follow directions describing the step by step experimental procedure.

Immunohistochemistry Protocol - Frozen for SignalStain® Boost Detection Reagent (Protocols)

Immunohistochemistry Protocol - Frozen for Boost Detection Reagent: easy to follow directions describing the step by step experimental procedure.

Immunohistochemistry Protocol - Paraffin for SignalStain® Boost Detection Reagent (Protocols)

Immunohistochemistry Protocol – Paraffin for Boost Detection Reagent: easy to follow directions describing the step by step experimental procedure.Immunohistochemistry Protocol - Paraffin for Boost Detection Reagent: easy to follow directions describing

Immunohistochemistry Protocol - Specific For Product: 12692 (Protocols)

Immunohistochemistry Protocol: easy to follow directions describing the step by step experimental procedure for product #12692.

Immunohistochemistry Technical Support

Cell Signaling Technology IHC technical support contact information and outline of requested information that our technical support specialists will need to assist you.

Immunohistochemistry Tips and Techniques

Learn how your Immunohistochemistry protocol affects your results.

Immunology/Inflammation (Pathway Diagram)

Expert-reviewed interactive pathways providing current overviews of NF-kB and Toll-like Receptor (TLR) signaling, as well as links to products from Cell Signaling Technology.

Immunoprecipitation Protocol (For Analysis By Kinase Assay) (Protocols)

Immunoprecipitation Protocol (For Analysis By Kinase Assay): easy to follow directions describing the step by step experimental procedure.

Immunoprecipitation Protocol (For Analysis By Western Immunoblotting) (Protocols)

Immunoprecipitation Protocol (For Analysis By Western Immunoblotting) : easy to follow directions describing the step by step experimental procedure.

Immunoprecipitation Protocol (For Native Protein) (Protocols)

Immunoprecipitation Protocol (For Native Protein): easy to follow directions describing the step by step experimental procedure.

Immunoprecipitation Protocol / (For Denatured Proteins) (IP / Denatured Protein) (Protocols)

Immunoprecipitation of Denatured Proteins Protocol: easy to follow directions describing the step by step experimental procedure.

Immunoprecipitation Protocol Utilizing Magnetic Separation (For Analysis By Western Immunoblotting) (Protocols)

Immunoprecipitation Protocol Utilizing Magnetic Separation (For Analysis By Western Blot): easy to follow directions describing the step by step experimental procedure.

Immunoprecipitation Troubleshooting Guide (Protocols)

Immunoprecipitation Troubleshooting Guide for easy to solve high and low background issues.

In-Cell Western Protocol (Protocols)

In-Cell Western Protocol: easy to follow directions describing the step by step experimental procedure.

In-Cell Western™ (Application Overviews)

In-cell Western: a simple method for quantification of intracellular signaling in whole cells. Data and links for tech support.

Interactive Human Kinome (Kinome Diagram)

Searchable Human Kinome showing the AGC, Tyrosine Kinases, TKL, CAMK, STE, CMGC, CK1 and atypical kinase groups.

IQ Protein Domain (Protein Domains)

A scientific resource for the IQ protein domain containing information on structure, function, and domain binding to calmodulin.

Jak and Cytokine Receptor Mutants in Cancer Table (Table Resources)

Jak and cytokine receptor mutations found in various cancers, along with the corresponding PubMed reference(s).

Jak/Stat Utilization Table (Table Resources)

The Jak/Stat Utilization Table displays the combinatorial use of tyrosine kinases and Stat proteins in cytokine/growth factor signaling.

Key Signaling Networks in Cancer

Cancer signaling pathways and research resources, including activation state antibodies and proteomic tools to discover post-translational modifications

Kinase Signaling (Pathway Diagram)

Expert-reviewed interactive pathway providing a current overview of ErbB/HER Signaling, a pathway description, select PubMed references, and links to PhosphoSitePlus.

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