Product Results

Chromatin IP Frequently Asked Questions (Application Overviews)

Chromatin IP (ChIP) Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.

Chromo Protein Domain (Protein Domains)

A scientific resource for the Chromo protein domain containing information on structure, function, and binding to methylated lysine residues during chromatin remodeling.

Cigall Kadoch, PhD: Science is a Team Sport

Cigall Kadoch, PhD: Specific, High Affinity Antibodies for Discovery

Cigall Kadoch, PhD: What Makes CST Unique

CiteAb Names Cell Signaling Technology "Antibody Company of the Year" and "Antibody Company Succeeding in Cancer Biology" (News Article)

CiteAb Names Cell Signaling Technology "Life Science Reagent Supplier of the Year" and "Antibody Validation Initiative" (News Article)

CiteAb Names Cell Signaling Technology "Researchers’ Choice" and "PTM Antibody Company of the Year" (News Article)

CiteAb Names Cell Signaling Technology, "Antibody Company of the Year" and "Researchers’ Choice" (News Article)

CK1 Protein Kinases Group (Kinome Diagram)

A kinome diagram showing the CK1 family of protein kinases.

CMGC Protein Kinases Group (Kinome Diagram)

A kinome diagram showing the CMGC group of protein kinases.

Co-IP Bait and Prey, and other applications of Immunoprecipitation (IP)

Commitment to Science

Summary description of CST with the mission statement and corporate commitment.

Common Pluripotency Markers

Highlighted common pluripotency markers with a brief description of their expression from Cell Signaling Technology

Commonly used Chemical Modulators Table (Table Resources)

Community Garden and Pollinator Protection

CST has a backyard garden program for employees to participate in.

Community Grants

Grant application guidelines and project description criteria for funding from CST.

Community Investment

A list of non-profit organizations and communities who have received support from Cell Signaling Technology

Complementary Technologies for Phospho-Peptide Enrichment

Concerns About Shellfish Growth Causes Local Nonprofits and Private Industry to Team Up to Test Rivers for CO₂ Levels (News Article)

Conferences & Events

Cell Signaling Technology events including the 2014 conference and vendor show listings.

Contribution of Extracellular Matrix to EMT (Pathway Diagram)

Contribution of Soluble Factors to EMT (Pathway Diagram)

Control Cell Extracts

Catalog numbers in tabular format for control cell extracts and proteins with links to product pages.

Control Treatments by Target (Control Table)

A list of recommended cell types and treatments to be used as positive and negative controls for activation state specific antibodies

Critical Considerations For Optimizing Imaging Mass Cytometry

CSD Protein Domain (Protein Domains)

A scientific resource for the CSD protein domain containing information on structure, function, and domain binding during chromatin remodeling.

CST Antibody Validation Principles (Process Explanations)

Antibody validation principles at Cell Signaling Technology.

CST Certificate of Analysis Search

CST CUT&RUN Kit: Validated for Flexibility

Learn how we have validated and optimized our CUT&RUN Kit to yield better signal-to-noise ratios, require fewer cells to analyze protein-DNA interactions, and be compatible with tissue samples. Get up to speed on all the protocol improvements we have mad

CST Data Sheet Search

CST Learning Lab LIVE! Webinar Series

CST Media Room

CST Partners with North Shore Technology Council to Promote Sustainability in Massachusetts-Based Life Science Organizations (News Article)

CST Proteomics Inquiries (Proteomics Overviews)

Fill out the form to contact the Proteomics Analytical Services team.

CST REMAINS OPEN DURING COVID-19 PANDEMIC

We Take Our Responsibility to You Seriously

CST Scientists Publish Results of Phosphoproteomic Study

Synopsis of CST scientists' publication in the journal Science Signaling describing phosphorylation patterns associated with non-small cell lung cancer (NSCLC).

CST Sponsors Beyond Benign to Expand Global Access to Green Chemistry Education (News Article)

CST Technical Documentation

Download the SDS, CoA, and Data Sheet for any CST product by searching with your CST product number.

CST Wins CiteAb 2023 Innovation Award for Anti-CAR Linker Antibodies for T-Cell Therapy, Named PTM Antibody Supplier of the Year (News Article)

CST肿瘤微环境主题系列讲座---第一讲：缺氧代谢与血管生成

CST肿瘤微环境主题系列讲座---第三讲：细胞粘附、细胞骨架、细胞基质、EMT

CST肿瘤微环境主题系列讲座---第二讲：肿瘤免疫微环境

CUE Protein Domain (Protein Domains)

A scientific resource for the CUE protein domain containing information on structure, function, and domain binding to ubiquitin in protein degradation pathways.

Custom Conjugation & Labeling Services

Custom-build antibody conjugates that match your assay requirements and deliver superior performance, and choose from a broad catalog of labels.

Custom ELISA Kits and Matched Antibody Pairs

Choose custom CST® ELISA products to match your project needs. Reserve lots, customize volumes or kit formats, order custom-matched antibody pairs, and more.

Custom Formulations Request

Many of our products are available in custom formulations. CST is happy to work with you to tailor products to meet the specialized needs of your experiments.

Custom Product Pricing Request

Consistent with the CST pledge to be a research partner, CST offers custom pricing for reagents needed in your assay.

Customer Support

Have a questions about an order? Contact a CST scientist via phone, email, or by submitting the form below.

Customized and Carrier-Free Formulations

Customized Products and Services

CST services combine CST's high-quality antibodies with expert scientific support.

Customized Proteomics Solutions for Expedited Drug Discovery

CUT&RUN Frequently Asked Questions (Application Overviews)

CUT&RUN Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.

CUT&RUN Kit Protocol (Protocols)

CUT&RUN Overview

CUT&RUN Protocol: A Visual Guide

CUT&RUN Resource Center

CUT&RUN Troubleshooting Guide (Protocols)

CUT&RUN: A New Way to Analyze Epigenetic Marks and Mechanisms

Cytokine Receptor Complexes and Activation

3D animated video tutorial illustrating IL-6 eceptor complex formation and activation.

Cytokines and Inflammation

Cytoskeletal Regulation and Vesicle Trafficking (Pathway Diagram)

Expert-reviewed interactive signaling pathways providing current overviews of the regulation of actin and microtubule dynamics, as well as links to products from CST.

Dako, an Agilent Technologies Company, and Cell Signaling Technology announce partnership within companion diagnostics (News Article)

DE&I Seminars and Programs

Death Protein Domain (Protein Domains)

A scientific resource for the death protein domain containing information on structure, function, and domain binding during apoptosis.

Death Receptor Signaling (Pathway Diagram)

Deciphering CAR-T Cells: Exploring Functional Mechanisms to Drive Next-Generation Immunotherapy

Deciphering epigenetic regulation of the immune response in cancer

Deciphering Epitranscriptomics: The importance of RNA modifications and RNA-binding proteins in disease

Uncovering the mechanisms underlying RNA modifications and RBP function are emerging frontiers in medicine that take the study of gene regulation a step beyond epigenetics

Deciphering Fibrosis: Drivers of Fibrotic Disease in the Liver and Heart

Understanding the underlying biology of fibrosis is critical for the diagnosis, treatment, and management of cardiac fibrosis, nonalcoholic steatohepatitis (NASH), and other fibrotic diseases

Deciphering Immuno-Oncology: Targeting Cellular Mechanisms of the Tumor Immune Response

Deciphering the cell cycle: The role of cell cycle control in cancer

Deciphering the Role of RNA-Binding Proteins in Neurodevelopment and Disease

DED Protein Domain (Protein Domains)

A scientific resource for the DED protein domain containing information on structure, function, and domain binding during apoptosis.

Detecting CAR Expression with Versatile, Innovative Antibodies

Developmental Biology Signaling (Pathway Diagram)

Overview of stem cell markers, lineage markers, development and differentiation signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources.

DH Protein Domain (Protein Domains)

A scientific resource for the DH protein domain containing information on structure, function, and domain binding during Rho GTPase activation.

Diffuse Intrinsic Pontine Glioma (DIPG)

Digestion of CUT&RUN Input DNA by MNase (Protocols)

Discounts for Discovery

Diversity in Science and STEM Scholarships

DNA Damage Response (Pathway Diagram)

DNA Library Prep for CUT&RUN: A Visual Guide

DNA Library Prep Kit for Illumina^® Protocol (ChIP-seq, CUT&RUN) (Protocols)

DNA Library Prep Kit for Illumina (ChIP-seq, CUT&RUN): easy to follow directions describing the step by step experimental procedure.

DNA Methylation (Pathway Diagram)

Expert-reviewed interactive diagram providing a current overview of DNA methylation, as well as links to products from CST.

Dopamine Signaling in Parkinson's Disease (Pathway Diagram)

Download Pathways by Disease Area (Pathway Diagram)

Resources include signaling pathways, antibodies and companion products, research overviews, technical resources, and recent review articles.

Downloadable Literature

Dr. Michael J. Comb Receives CiteAb Lifetime Achievement Award (News Article)

Dropping with the temps: Cool deals on CST mAbs

Education in Science Grants

CSTs commitment to Science Education: teacher grants for scientific education resources and summer internship programs.

EF-Hand Protein Domain (Protein Domains)

A scientific resource for the EF Hand protein domain containing information on structure, function, and calcium binding.

EH Protein Domain (Protein Domains)

A scientific resource for the EH protein domain containing information on structure, function, and domain binding during endocytosis and vesicle trafficking.

ELISA (Enzyme-linked Immunosorbent Assay) Detection Strategies

Three major categories of methods exist for detection in ELISA: colorimetric, fluorescent, and chemiluminescent. The type of substrate used depends on the needed assay sensitivity and on the signal-detection limits of the instrument used to read the plat

ELISA (Enzyme-linked Immunosorbent Assay) Test Results Interpretation

The following three types of analysis are used to analyze results from ELISA assays: qualitative, semiquantitative, and quantitative.

ELISA Protocol - Specific For Product: 12856 (Protocols)

ELISA Protocol for PathScan® Stress and Apoptosis Signaling Antibody Array Kit (Chemiluminescent Readout) #12856: easy to follow directions describing the step by step experimental procedure.

ELISA Protocol - Specific For Product: 12923 (Protocols)

ELISA Protocol for PathScan® Stress and Apoptosis Signaling Antibody Array Kit (Fluorescent Readout) #12923: easy to follow directions describing the step by step experimental procedure.

ELISA Resource Center

CST ELISA kits and reagents let you measure key cellular signaling nodes and other cellular target proteins using a wide selection of sandwich antibody assays.

ELISA-Peptide Assay Protocol (Protocols)

ELISA-Peptide Assay Protocol : easy to follow directions describing the step by step experimental procedure.

Employee Programs

Employee Volunteer Program

Engagement Committees and Events

ENTH Protein Domain (Protein Domains)

A scientific resource for the ENTH protein domain containing information on structure, function, and domain binding to phospholipids during endocytosis.

Environmental & Social Responsibility

The Corporate Social Responsibility of Cell Signaling Technology, Inc.

Environmental Grants

CST supports environmental projects and science education by providing small grants to local organizations.

Enzyme Immuno Assay Kit Protocol (Protocols)

Enzyme Immuno Assay Kit Protocol: easy to follow directions describing the step by step experimental procedure.

Enzyme-linked Immunosorbent Assay (ELISA) Components

In addition to the samples to be analyzed, other required materials in order to run a complete ELISA experiment include microplates, reagents, buffers, antibodies, and a plate reader.

Epigenetic Drivers and Regulators of Cancer

Epigenetic Drivers of Breast Cancer

Epigenetic Drivers of Leukemias

Epigenetic Drivers of Prostate Cancer

Epigenetic Writers and Erasers of Histone H3 (Pathway Diagram)

Epigenetic Writers and Erasers of Histones H2A, H2B, and H4 (Pathway Diagram)

Epigenetics (Pathway Diagram)

Overview of epigenetic and chromatin regulation pathways, antibodies and related reagents, interactive pathway diagrams, and technical resources for epigenetics research.

Equipment Reuse

ErbB/HER Signaling (Pathway Diagram)

Erk Antibody Comparison Table

Compare Cell Signaling Technology's Erk antibodies against one another to determine optimal applications

Erk Signaling (Product Type Overviews)

Phospho-Erk product lists, product citation lists, product selection tools, comparison tables and educational resources for MAPK signaling from Cell Signaling Technology.

EVH1 Protein Domain (Protein Domains)

A scientific resource for the EVH1 protein domain containing information on structure, function, and binding to a proline-rich motif to regulate actin dynamics.

Examples of Crosstalk Between Post-translational Modifications (Pathway Diagram)

Exceptional Performance of XP^® Monoclonal Antibodies (Product Type Overviews)

Case Study 4: Exceptional Performance of XP Monoclonal Antibodies in All Applications pertaining to eXceptional Monoclonal Technology (XMT) from Cell Signaling Technology.

Exceptional Reproducibility of XP^® Monoclonal Antibodies (Product Type Overviews)

Case Study 3: Exceptional Reproducibility of XP® Monoclonal Antibodies in All Applications pertaining to eXceptional Monoclonal Technology (XMT) from Cell Signaling Technology.

Exceptional Sensitivity of XP^® Monoclonal Antibodies (Product Type Overviews)

Case Study 2: Exceptional Sensitivity of XP Monoclonal Antibodies pertaining to eXceptional Monoclonal Technology (XMT) from Cell Signaling Technology.

Exceptional Specificity of XP^® Monoclonal Antibodies (Product Type Overviews)

Case Study 1: Exceptional Specificity of XP Monoclonal Antibodies pertaining to eXceptional Monoclonal Technology (XMT) from Cell Signaling Technology.

Experimental Design: Analyzing Intracellular Signaling With Flow Cytometry

Experimental Design: Controls for Immunofluorescence (IF)

F-Box Protein Domain (Protein Domains)

A scientific resource for the F-Box protein domain containing information on structure, function, and domain binding to ubiquitin in protein degradation pathways.

FastScan^® Sandwich ELISA Protocol (Colormetric ELISA) (Protocols)

FastScan™ ELISA (Enzyme-Linked Immunosorbent Assay) Kits

FastScan ELISA kits detect key signaling proteins using a solution-based assay format and are validated to ensure reproducible results across lots and users.

Feel the Flow: Immune Cell Signaling Cascades Reveal Phenotype and Function

FERM Protein Domain (Protein Domains)

A scientific resource for the FERM protein domain containing information on structure, function, and domain binding in cytoskeleton-associated proteins.

FF Protein Domain (Protein Domains)

A scientific resource for the FF protein domain containing information on structure, function, and binding to phospho-serine motifs.

FH2 Protein Domain (Protein Domains)

A scientific resource for the FH2 protein domain containing information on structure, function, and domain binding to actin.

FHA Protein Domain (Protein Domains)

A scientific resource for the FHA protein domain containing information on structure, function, and binding to phospho-serine and phospho-threonine motifs.

Fibrosis

Find alternatives to Santa Cruz antibodies

Use the lookup tool to find the CST equivalent for your SCBT product.

Flexible Spatial Biology Solution for Up to 8-Plex Amplification in Two Days: CST Launches SignalStar™ Multiplex IHC (News Article)

Flow Cytometry (F) Protocol for the Detection of Transcription Factors (Protocols)

Flow Cytometry (F) Protocol for the Detection of Transcription Factors with recommended companion products.

Flow Cytometry BrdU Modified Protocol (Protocols)

Flow Cytometry BrdU Modified Protocol: easy to follow directions describing the step by step experimental procedure.

Flow Cytometry Live Cell Protocol (Protocols)

Flow Cytometry Live Cell Protocol: easy to follow directions describing the step by step experimental procedure.

Flow Cytometry Protocol (Flow) (Protocols)

Flow Cytometry Protocol: easy to follow directions describing the step by step experimental procedure.

Flow Cytometry Protocol for Extracellular Staining Using Conjugated Secondary Antibodies (Protocols)

Flow Cytometry Protocol - Extracellular Staining - Conjugated Secondary Abs: easy to follow directions describing the step by step experimental procedure.

Flow Cytometry Protocol for FoxP3 on Human Peripheral Blood Mononuclear Cells (PBMC) (Protocols)

Flow Cytometry Protocol for FoxP3 on Human Peripheral Blood Mononuclear Cells (PBMC): easy to follow directions describing the step by step experimental procedure.

Flow Cytometry Protocol for FoxP3 on Murine Splenocyte T Cells (Protocols)

Flow Cytometry Protocol for FoxP3 on Murine Splenocyte T Cells: easy to follow directions describing the step by step experimental procedure.

Flow Cytometry Resource Center (Application Overviews)

Flow cytometry resources and products from CST Cell Signaling Technology

Flow Cytometry Technical Support (Protocols)

Technical support questions and issues for flow cytometry-validated antibodies and products from CST Cell Signaling Technology

Flow Cytometry Troubleshooting Guide (Protocols)

Troubleshooting tips for successfully performing Intracellular Flow Cytometry using CST recommended protocols and antibodies validated for Flow.

Flow Cytometry, FoxP3/Transcription Factor Fixation and Permeabilization Protocol (Protocols)

Flow Cytometry, Methanol Permeabilization Protocol (Protocols)

Flow Cytometry, Methanol Permeabilization Protocol: easy to follow directions describing the step by step experimental procedure.

Flow Cytometry, Triton™ X-100 Permeabilization Protocol (Protocols)

Flow Cytometry, Triton™ X-100 Permeabilization Protocol: easy to follow directions describing the step by step experimental procedure.

Fluorescent Multiplex Immunohistochemistry (mIHC) with Tyramide Signal Amplification Protocol (Protocols)

Protocol for Fluorescent Multiplex Immunohistochemistry (mIHC) with Tyramide Signal Amplification

Fluorescent Western Blotting Resources

Western blotting using fluorescent-conjugated secondary antibodies - accurate quantification and two-color multiplexing using primary antibodies from different species.

Fluorescent Western Immunoblotting Protocol (Primary Ab Incubation In BSA) (Protocols)

Fluorescent Western Immunoblotting Protocol (Primary Ab Incubation In BSA): easy to follow directions describing the step by step experimental procedure.

Fluorescent Western Immunoblotting Protocol (Primary Ab Incubation In Milk) (Protocols)

Fluorescent Western Immunoblotting Protocol (Primary Ab Incubation In Milk): easy to follow directions describing the step by step experimental procedure.

Formaldehyde vs. Alcohol Fixation for Immunofluorescence (IF)

Four Situations Where Flow Cytometry Can Help

Frequently Asked Questions

Frequently asked questions using our products while doing your research

FYVE Protein Domain (Protein Domains)

A scientific resource for the FYVE protein domain containing information on structure, function, and binding to phospholipids.

G-Protein-Coupled Receptors Signaling to MAPK/Erk (Pathway Diagram)

G1/S Checkpoint (Pathway Diagram)

G2M/DNA Damage Checkpoint (Pathway Diagram)

GAT Protein Domain (Protein Domains)

A scientific resource for the GAT protein domain containing information on structure, function, and domain binding to ubiquitin and GTP-bound ARF.

GEL Protein Domain (Protein Domains)

A scientific resource for the GEL protein domain containing information on structure, function, and domain binding to actin in cytoskeletal regulation.

General Inquiries

General Manager of Cell Signaling Technology China, Jay Dong, is Elected Co-President of Chinese Society for Cell Biology’s Academia-Industry Consortium for Innovation and Entrepreneurship (News Article)

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