A scientific resource for the TPR protein domain containing information on structure, function, and domain binding in cell cycle-associated proteins.
Trademark information appearing on Cell Signaling Technology website.
A scientific resource for the TRAF protein domain containing information on structure, function, and domain binding in TNFR Signaling.
Expert-reviewed diagram providing a current overview of the TREM2 pathway with references to its role in tumor development
A scientific resource for the TUBBY protein domain containing information on structure, function, and domain binding to DNA and phospholipids.
A scientific resource for the TUDOR protein domain containing information on structure, function, and domain binding to methylated-lysine residues in chromatin remodeling.
Video tutorials illustrate the science behind cellular processes and signaling pathways.
Several types of ELISAs have been developed: direct ELISA, indirect ELISA, sandwich ELISA, competitive ELISA, multiplex ELISA. The types of ELISAs are categorized based on the type of antibodies and enzymes used to bind the antigen of interest.
Graphical overview of the tyrosine kinase group of protein kinases featuring receptor and non-receptor (cytoplasmic) tyrosine kinases.
A scientific resource for the UBA protein domain containing information on structure, function, and domain binding to ubiquitin in protein degradation pathways.
Expert-reviewed interactive pathway providing a current overview of protein ubiquitination and proteasome degradation, as well as links to products from Cell Signaling Technology.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
A scientific resource for the UEV protein domain containing information on structure, function, and domain binding to ubiquitin.
A scientific resource for the UIM protein domain containing information on structure, function, and domain binding to ubiquitin.
Learn how to visualize protein expression in tissue with immunohistochemistry (IHC). See examples of successfully optimized IHC assays.
Neurodegeneration refers to disorders of the CNS that lead to loss of neurons or glia, and is associated with age-related diseases, autoimmune attacks on the nervous system, or genetic mutations that affect the heath of CNS cells.
RNA Regulation, Epitranscriptomics, and Disease | Cell Signaling Technology
Histone modification antibodies are validated using a peptide array assay at CST
3D animated video of vesicle trafficking and intracellular protein transport
A scientific resource for the VHL protein domain containing information on structure, function, and domain binding to hydroxylated proline residues.
A scientific resource for the VHS protein domain containing information on structure, function, and domain binding.
Cell Signaling Technology finds way to reduce our waste through recycling programs.
A scientific resource for the WD40 protein domain containing information on structure, function, and binding to both phospho-Ser/Thr and methylated lysine residues.
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This webinar will focus on how therapeutic interventions targeting dendritic cells can promote tumor immunity and enhance the efficacy of cancer therapy.
This webinar will focus on the potential role of innate immunity in neurodegeneration and cognitive function, particularly in Alzheimer's disease.
This webinar will focus on the importance of the immune regulatory context of the TME
This webinar describes how highly validated antibodies and mouse models can be used to study neurodegenerative conditions like Alzheimer's Disease.
Our antibodies are validated for WB and IP with detailed protocols, control extracts and troubleshooting guides. Download a free white paper and view detailed protocol and troubleshooting videos.
Western Immunoblotting Protocol: easy to follow directions describing the step by step experimental procedure.
Western Blotting (Fluorescent) Protocol: easy to follow directions describing the step by step experimental procedure.
Western Blotting-Conformation, LC Specific, Anti-Biotin Secondary Ab: easy to follow directions describing the step by step experimental procedure.
Western Blotting Protocol (Primary Ab Incubation In BSA): easy to follow directions describing the step by step experimental procedure.
Western Blotting Protocol (Primary Ab Incubation In Milk): easy to follow directions describing the step by step experimental procedure.
CST's Western Blotting Protocol shows you the critical experimental steps in western blotting and explains how small changes to the protocol can affect the final results.
Western Blotting troubleshooting guide for easy to solve high and low background issues.
CST's Western Blotting (WB) Troubleshooting Guide Video provides tips to help you diagnose experimental issues and offers recommendations to solve the problems.
Short videos from CST highlighting our optimized western blotting protocol and troubleshooting guide to diagnose issues and recommend solutions.
Recombinant antibodies offer several key advantages compared to traditional antibodies. These include superior lot-to-lot consistency, continuous supply, and amenability to antibody engineering.
An enzyme-linked immunosorbent assay (ELISA), or enzyme immunoassay (EIA), utilizes the specific interaction between an antibody and an antigen to selectively bind a substance that is most commonly peptides, proteins, antibodies, or hormones.
Discover how to successfully stain tissue with antibodies for immunohistochemistry (IHC) experiments. See examples of successfully stained IHC assays.
Understand when to use immunohistochemistry (IHC) over any other technique including Immunocytochemistry, Western Blot and ELISA
Download white paper guides to key CST applications: western blotting and iPSC generation.
A scientific resource for the WW protein domain containing information on structure, function, and domain binding to proline-rich motifs.
Performance characteristics of XP rabbit monoclonal antibodies from Cell Signaling Technology.
XTT Cell Viability Assay Protocol: easy to follow directions describing the step by step experimental procedure.
YAP is a critical mediator of the Hippo signaling pathway. See a performance comparison of YAP antibodies from CST and 2 other companies.
Antibody Application Insights: Tips and Tricks to Enhance your Research