Product Information
Captopril is supplied as a lyophilized powder. For a 20 mM stock, reconstitute 5 mg of powder in 1.15 ml of DMSO. Working concentrations and length of treatment can vary depending on the desired effect.
| Molecular Weight | 217.3 g/mol |
| Purity | >98% |
| Molecular Formula | C9H15NO3S |
| CAS | 62571-86-2 |
| Solubility | Soluble in DMSO at 20 mg/ml or water at 20 mg/ml. |
Captopril is a selective and reversible angiotensin-converting enzyme (ACE) inhibitor with an IC50 value of 0.022 μM (1). This small molecule selectively lowers angiotensin II, a hormone that when upregulated has been linked to increased hypertension, atherosclerosis, myocardial hypertrophy, and obesity (2-5). Captopril has also been shown to regulate inflammatory pathways as a reversible inhibitor of leukotriene A4 (LTA4) hydrolase, reducing leukotriene B4 synthesis (6).
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| Cat. # | Size | Qty. | Price |
|---|---|---|---|
| 53537S | 1 g |
|
