Much of the current research focuses on membrane/cell surface proteins, but traditional total proteome analysis identifies a relatively small number of these proteins due to competition from all other intracellular proteins in the samples. Proprietary methods developed by CST double the number of membrane proteins identified and quantified in a total proteome study, allowing for a more complete view of proteins on the cell surface.
CST also offers access to an internally-generated, membrane-enriched total proteome dataset with over 350 tumor samples from a variety of indications, and over 80 normal tissue samples.
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Source | Total Proteins | Cell Surface Proteins |
Literature | 11,000 | 1,300 |
CST | 11,000 | 2,600 |
Membrane-Enriched Total Proteome Service broadly surveys tumor specimens, identifying and quantifying twice as many cell surface proteins.