Overview of cell cycle and DNA damage signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources.
Overview of apoptosis signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources for apoptosis research.
PTMScan® Motif Antibody Kits
(Proteomics Overviews)
PTMScan® Motif Antibody Kits from Cell Signaling Technology
Control Treatments by Target
(Control Table)
A list of recommended cell types and treatments to be used as positive and negative controls for activation state specific antibodies
Histone Modification Table
(Table Resources)
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
Cellular Senescence
Cellular senescence is stable cell cycle arrest linked to aging and cancer and other disease states, including those associated with inflammation. It is induced by DNA damage, oncogenic signaling, and telomere shortening.
Protein and Pathway Abbreviations
(Table Resources)
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Ubiquitin Ligase Table
(Table Resources)
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
FHA Protein Domain
(Protein Domains)
A scientific resource for the FHA protein domain containing information on structure, function, and binding to phospho-serine and phospho-threonine motifs.
PI3K / Akt Substrates Table
(Table Resources)
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
Kinase-Disease Associations
(Table Resources)
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Human Oncogenes & Tumor Suppressor Genes
(Table Resources)
Summary of human oncogenes and tumor suppressor genes sorted by signaling pathway.
NF-κB Signaling
(Pathway Diagram)
G1/S Checkpoint
(Pathway Diagram)
Regulation of Apoptosis
(Pathway Diagram)
G2M/DNA Damage Checkpoint
(Pathway Diagram)