Overview of cell cycle and DNA damage signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources.
PTMScan® Motif Antibody Kits
(Proteomics Overviews)
PTMScan® Motif Antibody Kits from Cell Signaling Technology
Control Treatments by Target
(Control Table)
A list of recommended cell types and treatments to be used as positive and negative controls for activation state specific antibodies
Histone Modification Table
(Table Resources)
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
PI3K / Akt Substrates Table
(Table Resources)
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
Cellular Senescence
Cellular senescence is stable cell cycle arrest linked to aging and cancer and other disease states, including those associated with inflammation. It is induced by DNA damage, oncogenic signaling, and telomere shortening.
Kinase-Disease Associations
(Table Resources)
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Human Oncogenes & Tumor Suppressor Genes
(Table Resources)
Summary of human oncogenes and tumor suppressor genes sorted by signaling pathway.
Protein and Pathway Abbreviations
(Table Resources)
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
G2M/DNA Damage Checkpoint
(Pathway Diagram)