Cytokine Receptor Complexes and Activation
3D animated video tutorial illustrating IL-6 eceptor complex formation and activation.
Tutorials & Application Guides
Video tutorials illustrate the science behind cellular processes and signaling pathways.
Neuroinflammation in Neurodegenerative Diseases
Neuroinflammation is the activation of an immune response in the CNS by the microglia and astrocytes. While not linked mechanistically to neurodegenerative diseases, neuroinflammation is associated with the progression of Alzheimer's disease, Parkinson's
PTMScan® Multi-Pathway Service
(Proteomics Overviews)
Identifies and quantifies up to many hundreds of critical signaling nodes across pathways involved in cancer biology, immune cell signaling, and more.
Cellular Senescence
Cellular senescence is stable cell cycle arrest linked to aging and cancer and other disease states, including those associated with inflammation. It is induced by DNA damage, oncogenic signaling, and telomere shortening.
Download Pathways by Disease Area
(Pathway Diagram)
Resources include signaling pathways, antibodies and companion products, research overviews, technical resources, and recent review articles.
Immunology/Inflammation
(Pathway Diagram)
Expert-reviewed interactive pathways providing current overviews of NF-kB and Toll-like Receptor (TLR) signaling, as well as links to products from Cell Signaling Technology.
Jak/Stat Utilization Table
(Table Resources)
The Jak/Stat Utilization Table displays the combinatorial use of tyrosine kinases and Stat proteins in cytokine/growth factor signaling.
Kinase Signaling
(Pathway Diagram)
Expert-reviewed interactive pathway providing a current overview of ErbB/HER Signaling, a pathway description, select PubMed references, and links to PhosphoSitePlus.
