Cat. # | Size | Qty. | Price |
---|---|---|---|
4749T | 1 Kit (7 x 20 microliters) |
|
Product Includes | Quantity | Applications | Reactivity | MW(kDa) | Isotype |
---|---|---|---|---|---|
Integrin α5 Antibody 4705 | 20 µl |
|
H M Mk | 150 | Rabbit |
Integrin αV Antibody 4711 | 20 µl |
|
H R | 135, 140 | Rabbit |
Integrin β4 (D8P6C) XP® Rabbit mAb 14803 | 20 µl |
|
H | 210 | Rabbit IgG |
Integrin α4 (D2E1) XP® Rabbit mAb 8440 | 20 µl |
|
H M R | 70, 140, 150, | Rabbit IgG |
Integrin β1 (D2E5) Rabbit mAb 9699 | 20 µl |
|
H | 115, 135 | Rabbit IgG |
Integrin β3 (D7X3P) XP® Rabbit mAb 13166 | 20 µl |
|
H M | 100 | Rabbit IgG |
Integrin β5 (D24A5) Rabbit mAb 3629 | 20 µl |
|
H M R Mk | 90 | Rabbit IgG |
Anti-rabbit IgG, HRP-linked Antibody 7074 | 100 µl |
|
Rab | Goat |
Product Information
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser458 of human integrin α5 protein, Arg108 of human integrin αV. Antibodies are purified by protein A and peptide affinity chromatography. Monoclonal antibodies are produced by immunizing animals with a synthetic peptide sequence corresponding to residues surrounding Ser1027 of human integrin a4 protein, the carboxy terminus of human integrin β4 protein, Pro680 of human integrin b1 protein, Ile114 of human integrin b3 protein, and Lys789 of human β5 protein.
Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1,2). The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling) (1,2).
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